Routine HPV vaccination: Reflection on delivery strategies based on countries’ experiences

In this commentary, Waheed and colleagues reflect on HPV vaccine delivery strategies across several low- and middle-income countries, comparing country experiences against existing WHO guidelines. Three delivery approaches are documented: routinized campaign-mode vaccination using schools as the primary site (The Gambia, Zambia, Ethiopia), routine health facility services complemented by community and school outreach (Tanzania, Kenya, […]

Pandemic-related resilience in HPV vaccination programmes – Perspectives from selected countries in Africa on what it will take to vaccinate 90% of girls by 2030

In this series of five country case studies, Kouassi and colleagues document how Côte d’Ivoire, Kenya, Liberia, Zambia, and Senegal maintained and recovered their HPV vaccination programmes following COVID-19 disruptions. Common challenges included school closures, misinformation conflating HPV and COVID-19 vaccines, and competing health priorities that diverted staff and funding. Enabling factors included strong Ministry […]

Integrating HPV vaccine service delivery with adolescent health programmes – Experiences and perspectives from selected countries in Africa

In this case series, Ndiaye and colleagues describe how Senegal, Togo, Tanzania, and Lesotho have operationalized integrated HPV vaccine service delivery with adolescent health programmes. Across four countries, three models of integration emerge: incorporation into routine immunisation, co-delivery with non-vaccine adolescent health services (e.g., nutrition, deworming, sexual and reproductive health education), and leveraging new vaccine […]

Evidence for an HPV one-dose schedule

In this review, Stanley and colleagues examine the biological plausibility and clinical trial evidence supporting a single-dose HPV vaccination schedule. The authors synthesize data from randomized controlled trials—including KEN SHE (Kenya), DoRIS (Tanzania), the Costa Rica Vaccine Trial, and the IARC India trial—demonstrating high and durable efficacy comparable to multi-dose regimens. Post-licensure observational studies and […]

CHIC HPV Council Consensus Statement on One-Dose Recommendation

In this consensus statement dated April 28, 2022, the CHIC HPV Council welcomes the WHO SAGE conclusion that a single-dose HPV vaccine delivers solid protection comparable to two- or three-dose schedules, and urges national immunization programmes and policy bodies to act on this recommendation. The Council highlights benefits for girls and families (comparable protection), programme […]

Status of HPV disease and vaccination programmes in LMICs: Introduction to special issue

In this introduction to the special issue, Borda and colleagues present an overview of the current global epidemiology of cervical cancer incidence and mortality, with the highest burden concentrated in Africa and Asia. The article highlights decreased HPV vaccination coverage in recent years and underlines the need for new vaccine introductions and programme strengthening to […]

CHIC: Coalition to Strengthen the HPV Immunization Community – Briefing on HPV and Vaccination

This CHIC briefing document provides a concise overview of HPV disease burden, vaccination programmes, and key challenges facing low- and middle-income countries. It describes HPV as the most common sexually transmitted infection globally, responsible for over 630,000 new cancer cases and 311,000 deaths annually, with 530,000 being cervical cancers. The brief highlights that over 85% […]

HPV Vaccination Programs in LMICs from Asia & Western Pacific Regions Symposium – Report

This report summarizes the fourth CHIC symposium, held in Manila, Philippines (October 2–4, 2024), bringing together 95 participants from 17 countries across the Asia and Western Pacific regions. Participants included civil society organizations, Ministries of Health and Education, NGOs, NITAG members, EPI managers, and key global partners including WHO, UNICEF, Gavi, JSI, and PATH. The […]

Overview of CHIC symposia series: Summary of Africa and South Asia symposia

In this overview, Bolio and colleagues summarize the key challenges and lessons learned from the CHIC Africa (Addis Ababa, 2022) and South Asia (New Delhi, 2022) symposia, involving participants from 19 African and 7 South Asian countries. Topics covered include health information systems, Gavi applications, planning, stakeholder engagement, delivery platforms, and single-dose vaccination. The article […]

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