Human papillomavirus (HPV) vaccination is a cornerstone of cervical cancer prevention, particularly in low- and middle-income countries (LMICs), where the burden of disease remains high1. The World Health Organization (WHO) HPV Vaccine Introduction Clearing House reported that 147 countries (of 194 reporting) had fully introduced the HPV vaccine into their national schedules as of 20242. […]
Event Type: Publications
Barriers to HPV vaccine introduction and revitalization in sub-Saharan francophone African countries – A qualitative descriptive study
The pace of progress of HPV vaccine introduction in Sub-Saharan francophone African countries has been limited, particularly in conflict-affected countries. To better understand the barriers affecting the introduction and sustainability of the HPV vaccine, we conducted a qualitative study from January – April 2024 informed by insights from a multi-country HPV symposium. Our study explored […]
Case studies on the progress of cervical cancer screening programs in Bhutan, India, and Türkiye
In this case series, Burdier and colleagues describe the contrasting progress of cervical cancer screening programmes in Bhutan, India, and Türkiye, drawing on presentations from the CHIC South Asia Symposium (New Delhi, 2022). India, despite national VIA-based guidelines since 2016, reports only 1.9% ever-screened coverage among women aged 30–49, constrained by infrastructure gaps and absent […]
Effective communication by health care workers to promote HPV vaccination: Lessons learned from Kenya, India, and Nigeria
In this case study analysis, Njogu and colleagues examine how health care workers in Kenya, India, and Nigeria have communicated to promote HPV vaccine uptake at different stages of national rollout. In Kenya, a multisectoral approach and myth-busting training proved critical; in Sikkim (India), intensive social mobilization and cascade training underpinned a successful subnational introduction; […]
Accelerating and broadening multisectoral partnerships for introducing and rebuilding HPV vaccination programmes
In this commentary, Sidibe and colleagues propose a conceptual framework to guide countries in identifying and engaging stakeholders for HPV vaccine implementation. The framework organises actors into three tiers—key players, close supporters, and influencers—enabling systematic mapping across Ministries of Health and Education, civil society, professional associations, media, and the private sector. Drawing on experiences from […]
Routine HPV vaccination: Reflection on delivery strategies based on countries’ experiences
In this commentary, Waheed and colleagues reflect on HPV vaccine delivery strategies across several low- and middle-income countries, comparing country experiences against existing WHO guidelines. Three delivery approaches are documented: routinized campaign-mode vaccination using schools as the primary site (The Gambia, Zambia, Ethiopia), routine health facility services complemented by community and school outreach (Tanzania, Kenya, […]
Pandemic-related resilience in HPV vaccination programmes – Perspectives from selected countries in Africa on what it will take to vaccinate 90% of girls by 2030
In this series of five country case studies, Kouassi and colleagues document how Côte d’Ivoire, Kenya, Liberia, Zambia, and Senegal maintained and recovered their HPV vaccination programmes following COVID-19 disruptions. Common challenges included school closures, misinformation conflating HPV and COVID-19 vaccines, and competing health priorities that diverted staff and funding. Enabling factors included strong Ministry […]
Integrating HPV vaccine service delivery with adolescent health programmes – Experiences and perspectives from selected countries in Africa
In this case series, Ndiaye and colleagues describe how Senegal, Togo, Tanzania, and Lesotho have operationalized integrated HPV vaccine service delivery with adolescent health programmes. Across four countries, three models of integration emerge: incorporation into routine immunisation, co-delivery with non-vaccine adolescent health services (e.g., nutrition, deworming, sexual and reproductive health education), and leveraging new vaccine […]
CHIC Technical Brief on Country Decision-Making Factors: Expanding the Target Population for HPV Vaccination
This CHIC technical brief synthesizes evidence and programmatic considerations to guide country decision-making on expanding HPV vaccination beyond the primary target of girls aged 9–14, in response to a growing number of African countries adopting or considering vaccination of older girls (15–18), young women up to age 26, or boys. Grounding its analysis in WHO […]
Evidence for an HPV one-dose schedule
In this review, Stanley and colleagues examine the biological plausibility and clinical trial evidence supporting a single-dose HPV vaccination schedule. The authors synthesize data from randomized controlled trials—including KEN SHE (Kenya), DoRIS (Tanzania), the Costa Rica Vaccine Trial, and the IARC India trial—demonstrating high and durable efficacy comparable to multi-dose regimens. Post-licensure observational studies and […]