Routine HPV vaccination: Reflection on delivery strategies based on countries’ experiences

In this commentary, Waheed and colleagues reflect on HPV vaccine delivery strategies across several low- and middle-income countries, comparing country experiences against existing WHO guidelines. Three delivery approaches are documented: routinized campaign-mode vaccination using schools as the primary site (The Gambia, Zambia, Ethiopia), routine health facility services complemented by community and school outreach (Tanzania, Kenya, […]

Integrating HPV vaccine service delivery with adolescent health programmes – Experiences and perspectives from selected countries in Africa

In this case series, Ndiaye and colleagues describe how Senegal, Togo, Tanzania, and Lesotho have operationalized integrated HPV vaccine service delivery with adolescent health programmes. Across four countries, three models of integration emerge: incorporation into routine immunisation, co-delivery with non-vaccine adolescent health services (e.g., nutrition, deworming, sexual and reproductive health education), and leveraging new vaccine […]

Informations et données sanitaires pour l’action: Tanzanie

En Tanzanie, les systèmes d’information sanitaire constituent le socle de la planification et du suivi de la vaccination contre le HPV dans un pays de plus de 67 millions d’habitants et de plus de 12 000 formations sanitaires. Au niveau des établissements de santé, les outils papier restent en usage, tandis que du district vers […]

Panorama situationnel du HPV – Tanzanie

En Tanzanie, le programme HPV s’est développé en cinq phases distinctes : un projet pilote dans la région du Kilimandjaro (2014–15) ; une introduction nationale ciblant les filles de 14 ans (2018) ; HPV Plus intégrant l’hygiène menstruelle, la nutrition, le déparasitage et l’éducation à la santé sexuelle et reproductive (2019) ; une campagne multi-âges […]

Improving uptake of HPV Vaccine: Challenges and strategies used to reach Out-of-School Adolescents in Tanzania

In Tanzania, HPV vaccination coverage among out-of-school (OOS) adolescent girls aged 9–14 remains low despite national programme progress. As part of the SHARP mixed-methods implementation research study, 69 key informant interviews with health workers and managers in Mbeya and Arusha identified layered barriers to reaching OOS girls, including complex recruitment procedures, transport and distance constraints, […]

Health Information Systems and Data for Action: Tanzania

In Tanzania, health information systems underpin the planning and monitoring of HPV vaccination across a country of over 67 million people and more than 12,000 health facilities. At the facility level, paper-based tools remain in use, while from the district upward, the Vaccine Information Management System (VIMS) consolidates routine immunization reporting, vaccine stock data, and […]

Country Snapshot – Tanzania

In Tanzania, the HPV programme evolved through five distinct phases: a pilot in Kilimanjaro Region (2014–15); national introduction targeting 14-year-old girls (2018); HPV Plus integrating menstrual hygiene, nutrition, deworming, and sexual and reproductive health education (2019); a Multi-Age Cohort campaign targeting 5 million girls aged 9–14 (2024); and a switch to routine single-dose vaccination of […]

DoRIS Trial

Single-dose HPV vaccination in Tanzanian girls (9–14 years) achieved >98% seropositivity for HPV‑16/18 at 36 months. Antibody levels plateaued after 12 months and remained stable through 36 months, comparable to multi‑dose regimens. Avidity indices were similar across one‑, two‑, and three‑dose groups, indicating strong binding responses. Immunobridging showed single‑dose responses were non‑inferior to efficacy trials […]

Adolescent health integration with HPV vaccination programExperience from Tanzania

The presentation shared Tanzania’s journey introducing HPV vaccination nationally in 2018, following a 2014 pilot. Girls aged 9–14 receive two free doses, primarily through routine services and school outreach. Integration with adolescent health programs (nutrition, deworming, HIV) has improved coverage and resource use. Teachers play a key role in mobilization and tracking, while community engagement […]

One Dose Trial Data – DoriS Trial Results

Cette présentation met en lumière l’accumulation de données solides soutenant l’efficacité d’un schéma à une seule dose de vaccin contre le HPV, à partir d’études observationnelles (Costa Rica, Inde) et d’essais randomisés (DORIS en Tanzanie). Les résultats montrent que l’immunogénicité d’une seule dose est comparable à celle de deux ou trois doses, avec des réponses […]

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