The Q&A session examined lessons from past HPV vaccination challenges, focusing on misinformation crises in Ireland, Japan, and Mongolia. Participants stressed the need for rapid, decisive risk communication and stronger medical community support to prevent program collapses. Discussions highlighted cultural sensitivities around sexuality and parental perceptions influencing adolescent vaccination. Insights from HIV and COVID-19 campaigns emphasized proactive crisis management, transparent messaging, and leveraging trusted community figures. The role of counselors and school-based health ambassadors was noted as crucial for personalized engagement. Messaging reframed HPV immunization as cancer prevention rather than STI protection to increase acceptance.