The Q&A session focused on social mobilization and political engagement for Nigeria’s HPV vaccine introduction. Speakers highlighted that early advocacy with high-level authorities was crucial to ensure government support and program success. Major challenges included managing rumors and hesitancy, particularly among private schools, while public schools were more cooperative. The role of women’s associations and non-traditional partners was emphasized as key to improving community engagement. Lessons learned included the need to plan communication strategies early, anticipate urban-specific challenges (such as those seen in Lagos), and strengthen the involvement of schools and community structures in upcoming introduction phases.