This presentation reviewed global and regional strategies for HPV vaccine delivery, emphasizing school-based, outreach, and health facility platforms. It highlighted cost-effectiveness considerations (targeting $10–25 per fully vaccinated child) and the importance of equity-focused approaches to reach out-of-school girls. The speakers showcased integrated models like Tanzania’s HPV-Plus, combining vaccination with adolescent health services (nutrition, SRH education, deworming). They outlined India’s experience leveraging existing adolescent health programs (RBSK, RKSK) to boost Td and HPV coverage. Best practices stressed teacher engagement, tailored communication, and multi-sectoral coordination. The session concluded with calls for evidence generation, innovative service delivery, and robust monitoring to sustain HPV programs.