India’s Universal Immunization Program covers millions annually, drawing lessons from past campaigns (polio, MR, Mission Indradhanush, COVID-19). These campaigns demonstrated large-scale mobilization, real-time data capture (eVIN, CoWIN), and multi-platform delivery (schools, outreach, mobile teams). Upcoming HPV rollout targets 68M girls (9–14 years) via phased campaigns, followed by routine inclusion at age nine. Strategy prioritizes school-based delivery, out-of-school outreach, and geotagged microplanning with Ministry of Education support. Integration of digital tools for stock, session, and beneficiary tracking aims to ensure high coverage and minimize dropouts.