Emily Kobayashi (Gavi) outlined the transition to the Gavi 6.0 strategy during the 2025 CHIC Symposium. The intervention detailed the consolidation of multiple funding streams into a single holistic grant model and a unified cash envelope to enhance transparency and country sovereignty. Key policy shifts include the introduction of country vaccine budgets with financing ceilings and revised co-financing requirements for HPV multi-age cohort campaigns. To ensure sustainability, recommendations focus on integrating HPV delivery into broader health services, such as school nutrition and deworming programs, and optimizing vaccine portfolios with lower-cost products.