The presentation outlines Ethiopia’s HPV vaccine delivery approach, emphasizing school-based campaigns complemented by outreach for out-of-school and pastoralist communities. It details achievements since 2018, including vaccination coverage trends and strategies adopted during COVID-19 disruptions. Key enablers include political commitment, inter-sectoral collaboration, and tailored communication efforts to address equity and misinformation. Lessons learned highlight the need for sustainable planning, integrated services, and continued partner engagement for long-term coverage gains.