Global overview on available assays for screening and treatment options for cervical cancer

The presentation outlined WHO’s global strategy to eliminate cervical cancer, aiming for an incidence below four per 100,000 women through 90-70-90 targets by 2030. It traced the evolution of WHO guidelines (2011–2021), emphasizing HPV DNA testing, ablative treatments (cryotherapy, thermal ablation), and simplified screen-and-treat algorithms. Distinctions for women living with HIV include earlier and more frequent screening intervals. Emerging tools—mRNA testing, dual-stain cytology, AI, and self-sampling—are being reviewed under the “living guidelines” model for rapid evidence updates. Validation of HPV tests remains critical, as only 60% of 254 available assays have peer-reviewed evidence. Scaling up requires integration with reproductive health services, point-of-care solutions, and robust implementation research to ensure high coverage and treatment retention.

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Media: Video