During the discussion, participants raised questions about how Burkina Faso achieved high HPV vaccination coverage despite insecurity, requesting details on community and political engagement, logistical strategies, and partner support. Concerns were voiced on parental consent, especially for school-based delivery, and on managing misinformation, adverse events, and data reliability in conflict zones. Senegal and Côte d’Ivoire highlighted their adaptations, including teacher involvement, use of religious leaders, and integration of campaigns with other vaccines. Key lessons emphasized multisectoral collaboration, tailored communication, flexible service delivery, and documentation of good practices to maintain trust and improve program reach.