The presentation outlines culturally sensitive communication strategies for HPV vaccination targeting girls aged 9–14 in India. It highlights challenges such as limited awareness, myths, and parental resistance, particularly among out-of-school girls. Strategies emphasize contextualized messaging, youth involvement, and leveraging school ambassadors, community leaders, and faith influencers. Integration with existing adolescent health programs and convergence across sectors is critical. Digital platforms, community radio, and self-help groups are key tools for outreach. A mix of interpersonal, mass, and social media approaches ensures broad and culturally resonant engagement.