The CHIC Symposium on HPV for Southeast Asia and the Pacific gathered 95 delegates from 17 countries in Manila to exchange strategies, challenges, and successes in vaccination programs. Discussions emphasized cultural understanding, political advocacy, and the shift toward single-dose regimens to improve coverage and sustainability. Delegates highlighted collaborative approaches for securing vaccine supply chains, addressing hard-to-reach populations, and adapting innovations to national contexts. The meeting underscored a shared commitment to eliminating cervical cancer through coordinated regional efforts.