The CHIC online meeting convened stakeholders to share experiences on HPV vaccination programs, focusing on progress, challenges, and new strategies across African countries. Côte d’Ivoire reported moving from a two-dose to a single-dose schedule and strengthening community engagement; Cameroon shared its integration of male vaccination and school outreach; Kenya presented its success in achieving 78% first-dose coverage through school and media partnerships; and Nigeria outlined its phased national introduction plan starting September. Discussions emphasized addressing vaccine hesitancy, strengthening data systems, and ensuring sustainability through cross-country collaboration.