The policy analysis examines Indonesia’s rapid HPV vaccine scale-up from 20 districts in 2016 to nationwide implementation in 2023, guided by a health policy triangle framework. Key milestones included joint decrees across four ministries, prioritization of domestic vaccine production, and multi-actor engagement with technical support. Policies evolved to strengthen agenda-setting, health systems, and community awareness, while addressing regulatory frameworks for rollout. The process highlighted scientific evidence, domestic production, and intersectoral collaboration as drivers of success. Future challenges include sustaining political support and preparing for evolving government structures and financing needs