The presentation from Togo’s Ministry of Health outlines the decision-making and implementation process for introducing a single-dose HPV vaccination schedule. It details national cancer control strategies and the pilot project conducted between 2015–2017 targeting 10-year-old girls in two districts, achieving over 99% coverage. Following global recommendations and GAVI support, Togo adopted the single-dose schedule in 2023. The campaign targeted girls aged 10–14 and routine vaccination for 9-year-olds, leveraging school-based strategies due to high enrollment rates. Multi-sectoral collaboration, community mobilization (including Red Cross involvement), and integration with adolescent health initiatives were emphasized. Preliminary results show 46% coverage during the 5-day campaign, with lessons on communication and rumor management highlighted for future scale-up.